Journal Issue: Am J Cancer Res Volume 15(2);  2025

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Journal List

Volume 15(2);  2025

Review Articles

Advances and potentials in platelet-circulating tumor cell crosstalk
Jie Yang, Pingyao Xu, Guiji Zhang, Dongsheng Wang, Bo Ye, Lichun Wu
Am J Cancer Res. 2025; 15(2): 407–425. Published online 2025 Feb 15. doi: 10.62347/JAYK5667
PMCID:
PMC11897628
Abstract Article PDF–1.1M
Microporous annealed particle hydrogels in cell culture, tissue regeneration, and emerging application in cancer immunotherapy
Junjie Wang, Qin Zhang, Liwen Chen
Am J Cancer Res. 2025; 15(2): 665–683. Published online 2025 Feb 15. doi: 10.62347/WRGW4430
PMCID:
PMC11897623
Abstract Article PDF–2.4M

Original Articles

SCARA5 might be one potential marker for CC and promoted Ferroptosis by FTL
Wenjing Qi, Shunan Zhang
Am J Cancer Res. 2025; 15(2): 426–438. Published online 2025 Feb 15. doi: 10.62347/CGEJ9093
PMCID:
PMC11897624
Abstract Article PDF–3.4M
Combined impact of prognostic nutritional index, fibrinogen-to-albumin ratio, and neutrophil-to-lymphocyte ratio on surgical outcomes and prognosis in hepatocellular carcinoma
Liuhaonan Zeng, Yixun Tang, Xiaoling Huang, Wanmin Pei, Yongqiong Liao, Jitong Liu
Am J Cancer Res. 2025; 15(2): 439–451. Published online 2025 Feb 15. doi: 10.62347/RTMF3105
PMCID:
PMC11897630
Abstract Article PDF–830K
GDF15 promotes the resistance of epithelial ovarian cancer cells to gemcitabine via DHCR24-mediated cholesterol metabolism to elevate ABCB1 and ABCC1 levels in lipid rafts
Linlin Guo, Yan He, Huang Xin
Am J Cancer Res. 2025; 15(2): 452–469. Published online 2025 Feb 15. doi: 10.62347/KYIY8286
PMCID:
PMC11897626
Abstract Article PDF–17M
Development and validation of a prediction model for myelosuppression in lung cancer patients after platinum-based doublet chemotherapy: a multifactorial analysis approach
Xueyan Li, Linyu Li, Lu Zhang
Am J Cancer Res. 2025; 15(2): 470–486. Published online 2025 Feb 15. doi: 10.62347/TFUC2568
PMCID:
PMC11897629
Abstract Article PDF–3.5M
Tumor bearing in untreated breast cancer decreases exercise tolerance without lowering maximal oxygen uptake in rats
Ramona E Weber, Kiana M Schulze, Nathan J Kenney, Britton C Scheuermann, Olivia N Kunkel, Carl J Ade, Timothy I Musch, Brad J Behnke, David C Poole
Am J Cancer Res. 2025; 15(2): 487–500. Published online 2025 Feb 15. doi: 10.62347/QCCZ2316
PMCID:
PMC11897639
Abstract Article PDF–873K
Dissecting the high-risk property of 1q gain/amplification in patients with newly diagnosed multiple myeloma
Xinyue Liang, Weiling Xu, Fan Zhou, Wenyang Huang, Xingcheng Yi, Yingjie Zhang, Yurong Yan, Nan Zhang, Jingxuan Wang, Xiaoxiao Sun, Rui Hu, Yufeng Zhu, Xintian Ma, Yue Sun, Maozhou Lan, Mengtuan Long, Shaji K Kumar, Yun Dai, Fengyan Jin
Am J Cancer Res. 2025; 15(2): 501–516. Published online 2025 Feb 15. doi: 10.62347/FXVH4425
PMCID:
PMC11897644
Abstract Article PDF–1.9M
Key prognostic factors in transarterial chemoembolization combined with sorafenib treatment for hepatocellular carcinoma with portal vein tumor thrombosis
Zilun Lei, Hao Chai, Xiaoya Liu, Yingsong Jiang
Am J Cancer Res. 2025; 15(2): 517–532. Published online 2025 Feb 15. doi: 10.62347/SXMJ5155
PMCID:
PMC11897632
Abstract Article PDF–2.8M
Potential benefits of combined treatment with Hsp90 inhibitor AUY922 and cisplatin for overcoming drug resistance in nasopharyngeal carcinoma
William C Cho, Chi F Wong
Am J Cancer Res. 2025; 15(2): 533–545. Published online 2025 Feb 15. doi: 10.62347/OSGO7209
PMCID:
PMC11897633
Abstract Article PDF–4.0M
Plasma exosomal miR-150-3p, NMT2, and PRDM1 as predictive biomarkers of acute tumor response in patients with cervical cancer undergoing chemoradiotherapy
Oyeon Cho
Am J Cancer Res. 2025; 15(2): 546–558. Published online 2025 Feb 15. doi: 10.62347/SPQY5709
PMCID:
PMC11897638
Abstract Article PDF–3.7M
Cost-effectiveness analysis of trilaciclib for preventing myelosuppression in small cell lung cancer patients treated with etoposide, carboplatin, and atezolizumab
Xiaoya Hu, Mingpu Liu, Yuanli Wu, Weiying Zhou, Hongmei Wang
Am J Cancer Res. 2025; 15(2): 559–572. Published online 2025 Feb 15. doi: 10.62347/SNXD3155
PMCID:
PMC11897622
Abstract Article PDF–3.1M
Risk factors for immunoresistance in advanced non-small cell lung cancer and the advantages of targeted therapy in improving prognosis
Ping Yang, Shangxiang He, Linyin Fan, Ling Ye, Heng Weng
Am J Cancer Res. 2025; 15(2): 573–586. Published online 2025 Feb 15. doi: 10.62347/FGAY1920
PMCID:
PMC11897627
Abstract Article PDF–1.5M
Predictive value of CT radiomics and inflammatory markers for pulmonary adenocarcinoma spread through air spaces
Changlei Lv, Guoping Zhang, Bingqiang Xu, Minggang Huang, Yan Zhang, Mingqing Kou
Am J Cancer Res. 2025; 15(2): 587–600. Published online 2025 Feb 15. doi: 10.62347/UBDR6353
PMCID:
PMC11897614
Abstract Article PDF–1.4M
Overcoming challenges of recruiting cancer patients into clinical trials: insights from a randomized trial of app-based smoking cessation interventions
Margarita Santiago-Torres, Johann Lee Westmaas, Jamie S Ostroff, Kristin E Mull, Brianna M Sullivan, Joseph M Unger, Jonathan B Bricker
Am J Cancer Res. 2025; 15(2): 601–617. Published online 2025 Feb 15. doi: 10.62347/SPVK4847
PMCID:
PMC11897642
Abstract Article PDF–1.7M
Impact of long-term N-acetylcysteine use on cancer risk
Cherng-Chia Yang, Wan-Ming Chen, Ben-Chang Shia, Szu-Yuan Wu
Am J Cancer Res. 2025; 15(2): 618–630. Published online 2025 Feb 15. doi: 10.62347/VCDJ1296
PMCID:
PMC11897643
Abstract Article PDF–1.3M
Efficacy of a combination of O-RADS, CEUS, and CA125, in identification of ovary-adnexal malignant lesions
Juan Zhang, Ruili Wang, Xiaoxiao Duan, Juan Chen
Am J Cancer Res. 2025; 15(2): 631–642. Published online 2025 Feb 15. doi: 10.62347/JHJJ1149
PMCID:
PMC11897641
Abstract Article PDF–904K
Comparative study between single modality radiotherapy and concurrent chemoradiation for selected patients with early-stage laryngeal cancer
Fatma Gharib, Mostafa Ammar, Ahmed S Elhamshary, Mohamed Sheta, Wael Mansour, Asma M Elkady
Am J Cancer Res. 2025; 15(2): 643–651. Published online 2025 Feb 15. doi: 10.62347/BSYZ7959
PMCID:
PMC11897616
Abstract Article PDF–639K
Association between psychological resilience and symptom burden in postoperative patients with brain gliomas and its influencing factors
Yanan Jing, Chan Liu, Lijun Wang, Xiaoxi Liu, Lei Wang
Am J Cancer Res. 2025; 15(2): 652–660. Published online 2025 Feb 15. doi: 10.62347/QTZW9567
PMCID:
PMC11897625
Abstract Article PDF–477K
A novel gemcitabine analog as a potential anticancer agent: synthesis and in-vitro evaluation against pancreatic cancer
Joy Okoro, Raviteja Bulusu, Esther Frimpong, Xue Zhu, Sherise Rogers, Edward Agyare
Am J Cancer Res. 2025; 15(2): 684–704. Published online 2025 Feb 15. doi: 10.62347/KXSR8930
PMCID:
PMC11897620
Abstract Article PDF–5.2M
Sociodemographic characteristics associated with pancreatic cancer incidence and mortality among Blacks in the United States: a SEER-based study
Esther Frimpong, Eugene Annor, Raviteja Bulusu, Joy Okoro, Gebre-Egziabher Kiros, Renee Reams, Edward Agyare
Am J Cancer Res. 2025; 15(2): 705–722. Published online 2025 Feb 15. doi: 10.62347/GJCX1238
PMCID:
PMC11897636
Abstract Article PDF–2.3M
Radiotherapy can significantly improve survival outcomes in patients with muscle-invasive bladder cancer who are unsuitable for cystectomy or chemoradiotherapy
Nai-Wen Kang, Kuei-Li Lin, Kai-Yuan Lin, Yin-Hsun Feng, Chung-Han Ho, Yi-Chen Chen, Ching-Chieh Yang
Am J Cancer Res. 2025; 15(2): 723–736. Published online 2025 Feb 15. doi: 10.62347/XLPX5541
PMCID:
PMC11897634
Abstract Article PDF–1.7M
Association of concomitant MASLD and hepatitis B virus with clinical prognosis in hepatocellular carcinoma after curative resection
Chih-Jan Ko, Hung-Yu Lin, Pei-Min Hsieh, Wen-Lung Wang, Szu-Ying Chen, Li-Wei Chou, Yaw-Sen Chen, Yu-Wei Huang, Wen-Chao Ho, Chih-Wen Lin
Am J Cancer Res. 2025; 15(2): 737–748. Published online 2025 Feb 15. doi: 10.62347/KSLN5850
PMCID:
PMC11897618
Abstract Article PDF–644K
Patho-Net: enhancing breast cancer classification using deep learning and explainable artificial intelligence
Kalappanaickenpatty Suriaprakasam Manojee, Athiappan Rajiv Kannan
Am J Cancer Res. 2025; 15(2): 754–768. Published online 2025 Feb 15. doi: 10.62347/XKFN1793
PMCID:
PMC11897615
Abstract Article PDF–3.3M
Random survival forest model in patients with epithelial ovarian cancer: a study based on SEER database and single center data
Luwei Wei, Guowei Chen, Huiying Liang, Li Li
Am J Cancer Res. 2025; 15(2): 769–780. Published online 2025 Feb 15. doi: 10.62347/PLDH8547
PMCID:
PMC11897640
Abstract Article PDF–2.2M
Predictive nomogram for risk of pulmonary infection in lung cancer patients undergoing radiochemotherapy: development and performance evaluation
Yujie Huang, Guang Han
Am J Cancer Res. 2025; 15(2): 781–796. Published online 2025 Feb 15. doi: 10.62347/MQQB5184
PMCID:
PMC11897617
Abstract Article PDF–3.1M
Nomogram integrating clinical-radiological and radiomics features for differentiating invasive from non-invasive pulmonary adenocarcinomas presenting as ground-glass nodules
Ning Dong, Sirong Wei, Lei Zheng, Delong Huang, Guowei Zhang, Yunxin Li, Hu Zhang, Aijie Wang, Ranran Huang, Xinyao Zhao, Peng Liang
Am J Cancer Res. 2025; 15(2): 797–810. Published online 2025 Feb 15. doi: 10.62347/AOAN9966
PMCID:
PMC11897637
Abstract Article PDF–1.9M
Comparing health insurance-reimbursed lenvatinib and self-paid atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma
Yuan-Hung Kuo, Yen-Hao Chen, Ming-Chao Tsai, Sheng-Nan Lu, Tsung-Hui Hu, Chao-Hung Hung, Chien-Hung Chen, Jing-Houng Wang
Am J Cancer Res. 2025; 15(2): 811–823. Published online 2025 Feb 15. doi: 10.62347/BYIE2654
PMCID:
PMC11897613
Abstract Article PDF–1.2M
Evaluation of a tumor marker gastrin-releasing peptide precursor in the patients with kidney injuries
Nan Duan, Zhihui Li, Zhiyan Li, Lu Pang, Jialin Du, Le Chang, Haiming Huang, Haixia Li
Am J Cancer Res. 2025; 15(2): 824–832. Published online 2025 Feb 15. doi: 10.62347/CBSP3728
PMCID:
PMC11897619
Abstract Article PDF–569K

Case Report

Pediatric nasal septum pleomorphic adenoma: a case report
Jialian Feng, Yatian Liu, Jianguo He, Xiao Jiao
Am J Cancer Res. 2025; 15(2): 661–664. Published online 2025 Feb 15. doi: 10.62347/PNUH7125
PMCID:
PMC11897635
Abstract Article PDF–671K

Brief Communication

Early-phase clinical trials in the pandemic era: a four-year experience from an academic cancer center
Katie Moreland, Bethany Fuhrman, Kayla Webb, Melanie Margraf, Jessica Wernke, Christine Vollmer, Alison Kastl, Michelle Marcum, Jennifer Leddon, Amanda Jackson, Emily Curran, Shesh Rai, Trisha Wise-Draper, Davendra Sohal
Am J Cancer Res. 2025; 15(2): 749–753. Published online 2025 Feb 15. doi: 10.62347/AXBC8427
PMCID:
PMC11897621
Abstract Article PDF–213K

Erratum

Monepantel considerably enhances the therapeutic potentials of PEGylated liposomal doxorubicin and gemcitabine in ovarian cancer: in vitro and in vivo studies
Parvin Ataie-Kachoie, Krishna Pillai, Samina Badar, Javed Akhter, David Lawson Morris
Am J Cancer Res. 2025; 15(2): 833–834. Published online 2025 Feb 15. doi: 10.62347/VVPS6907
Corrects:
Am J Cancer Res. 2018; 8(10): 2064–2075.
PMCID:
PMC11897631
Correction PDF–677K
Articles from American Journal of Cancer Research are provided here courtesy of e-Century Publishing Corporation